Meclizine or Bonine vs Gravol: Different Drugs, and a Border Problem
Gravol is dimenhydrinate. Gravol's own site says dimenhydrinate is the active ingredient in all Gravol and Gravol Kids products, and that Gravol Ginger contains ginger instead. Meclizine is a different antihistamine, sold in the United States as Bonine and as Dramamine Less Drowsy. The complication is geography: meclizine is no longer manufactured for sale in Canada and is no longer available there under any brand name, which is why a Canadian shopper comparing the two is usually choosing between one product and nothing. Canadian pharmacy monographs were checked in September 2026 and availability changes, so ask your pharmacist what is actually stocked. Which medicine suits you is a question for your doctor or pharmacist, and if you would rather skip antihistamines, a drug-free option like Dizzout exists too.
Key facts
- Gravol's own site says dimenhydrinate is the active ingredient in all Gravol and Gravol Kids products, and that Gravol Ginger contains ginger instead.
- Meclizine is a different antihistamine: the Bonine label and the Dramamine Less Drowsy label both list Meclizine HCl 25 mg.
- Bonine vs Gravol and Bonamine vs Gravol are the meclizine vs Gravol question under other names: Bonine is an American brand of meclizine, and Bonamine was its Canadian name.
- Canadian pharmacy monographs state that meclizine is no longer manufactured for sale in Canada, and Health Canada's Drug Product Database lists Bonamine, its old Canadian brand, as cancelled.
- On the American labels, dimenhydrinate allows 1 to 2 tablets every 4 to 6 hours and warns that marked drowsiness may occur, while meclizine is 1 to 2 tablets once daily and its label warns of drowsiness without the word marked.
Meclizine and Gravol are not the same medicine, and the difference is not subtle. Gravol is the Canadian brand name for dimenhydrinate, the same active ingredient sold in the United States as Dramamine Original. Meclizine is a separate antihistamine, sold in the United States under the Bonine and Dramamine Less Drowsy names, and as plain store-brand meclizine. If you searched for Bonine or Bonamine vs Gravol, it is the same question: Bonine is an American brand of meclizine, and Bonamine was its Canadian name.
There is a second answer sitting underneath the first one, and it is the reason this comparison confuses people. If you are in Canada, you can buy Gravol in any supermarket, and you will not find meclizine at all. It is no longer manufactured for the Canadian market. So the comparison a Canadian shopper is actually making, most of the time, is between the box in front of them and a product they read about on an American website. This page lays out both halves: what the two drugs are, and what you can realistically get where you are.
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Gravol, meclizine and Dizzout, by label-level facts and where you can buy them
| Feature | Gravol (dimenhydrinate) | Meclizine (Bonine, Dramamine Less Drowsy) | Dizzout |
|---|---|---|---|
| Active ingredient | Dimenhydrinate, per Gravol's own FAQ | Meclizine HCl 25 mg on the Dramamine Less Drowsy label | None, it is not a drug |
| Sold in Canada | Yes, it is the common Canadian brand | No, monographs say it is no longer manufactured for sale there | Yes, it is an app store download |
| Sold in the United States | Yes, Gravol itself is marketed there, alongside Dramamine Original and store-brand dimenhydrinate | Yes, as Bonine, Dramamine Less Drowsy and store brands | Yes, on iOS and Android |
| Dosing on the American label of the same ingredient | 1 to 2 tablets every 4 to 6 hours, max 8 in 24 hours | 1 to 2 tablets once daily | No dosing interval, use it again when you need it |
| Drowsiness wording | Marked drowsiness may occur | Drowsiness may occur | No antihistamine, so no drowsiness |
| Ginger versions | Gravol Ginger contains ginger, not dimenhydrinate | Dramamine also sells a ginger product with no antihistamine | Not applicable |
| Prescription needed | No, sold over the counter in Canada | No in the US, but a pharmacist conversation in Canada | No, it is an app |
| Cost | Whatever the box costs | Whatever the box costs, where it is stocked | Free to download; full access $7.99/mo or $49.99/yr, or $3.99 for 15 listens |
Gravol is dimenhydrinate, and meclizine is something else
Gravol's own FAQ states that dimenhydrinate is an antihistamine for nausea, vomiting and dizziness due to motion sickness, and that it is the active ingredient in all Gravol and Gravol Kids products. The same FAQ notes that Gravol Ginger does not contain dimenhydrinate, and that its active ingredient is ginger, which is worth knowing if you have picked up the wrong box in a hurry.
Meclizine is a different antihistamine in the same broad family. In the United States it appears as Bonine, as Antivert, as store-brand meclizine, and as Dramamine Less Drowsy, whose Drug Facts panel lists Meclizine HCl 25 mg. So "meclizine vs Gravol" is a comparison of two distinct active ingredients, in a way that "dimenhydrinate vs Gravol" is not: dimenhydrinate is simply what is inside Gravol.
The part nobody tells you: meclizine is not sold in Canada
Canadian pharmacy drug monographs state plainly that meclizine is no longer being manufactured for sale in Canada and is no longer available under any brand name. The brand it used to be sold under there was Bonamine. A Canadian travel pharmacy describes the same situation from the other side, saying Bonamine was discontinued by the manufacturer and that it now obtains meclizine from a compounding pharmacy that makes medicines the manufacturers no longer supply.
That changes what this comparison is for. If you are in the United States, meclizine and dimenhydrinate are both on the shelf and choosing between them is a genuine decision. If you are in Canada, Gravol is the one you can buy, and getting meclizine means a conversation with a pharmacist about compounding or about what to do instead. Availability moves, and a monograph is not a promise about your local shop, so ask before you plan around it.
Where you can buy both, here is how the labels differ
The clearest way to compare the two drugs is through the two American Dramamine boxes, because they carry the same brand and different ingredients, and both labels are public. Dramamine Original Formula lists Dimenhydrinate 50 mg, the same active ingredient as Gravol, and directs adults and children 12 and over to 1 to 2 tablets every 4 to 6 hours with a maximum of 8 tablets in 24 hours. Its warning says marked drowsiness may occur.
Dramamine Less Drowsy lists Meclizine HCl 25 mg and directs the same age group to 1 to 2 tablets once daily. Its warning says drowsiness may occur, without the word marked, and it says not to give it to children under 12 unless a doctor directs it. Both labels tell you to take the first dose half an hour to an hour before you start. Canadian Gravol packaging carries its own directions, which may not match the American dimenhydrinate label, so read the box you are holding and ask your pharmacist rather than assuming the two match.
If you would rather not take an antihistamine, or cannot get the one you wanted
Dizzout is a drug-free motion sickness app, and it is available in the same places on both sides of the border because it is not a pharmacy product. There is no active ingredient. It plays precisely calibrated audio through any headphones you already own, wired or Bluetooth, with no special hardware, and relief comes in about 90 seconds. There is no drowsiness because there is no antihistamine, and there is no waiting period between uses.
It runs on iOS and Android. It is free to download, and full access is a paid subscription at $7.99 per month or $49.99 per year, with a $3.99 option for 15 listens if you only need it for one trip. It is not a replacement for medicine and not medical advice, and we do not claim it works better than any drug. For someone in Canada who went looking for meclizine and found an empty shelf, it is simply one more thing worth knowing exists.
When to use which
If you are in the United States, both drugs are on the shelf and the choice is a real one: dimenhydrinate with a repeat dose allowed every 4 to 6 hours and a stronger drowsiness warning, or meclizine once daily with a milder one. If you are in Canada, Gravol is what you can buy, and meclizine means asking a pharmacist about compounding or about a different plan entirely. Neither of those decisions belongs to a website. Which medicine is appropriate for you, for a child, for an older adult or during pregnancy is a medical question, so ask your doctor or pharmacist and follow the product label. If you would rather avoid antihistamines, or you are staring at a shelf that does not stock the thing you came for, a drug-free option like Dizzout is worth considering alongside that advice.
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Frequently asked questions
Is Gravol the same as meclizine?
No. Gravol's own site says dimenhydrinate is the active ingredient in all Gravol and Gravol Kids products. Meclizine is a different antihistamine, sold in the United States as Bonine and as Dramamine Less Drowsy. The American product that matches Gravol is Dramamine Original Formula, which lists Dimenhydrinate 50 mg, not Dramamine Less Drowsy.
Is Bonine the same as Gravol?
No. Bonine is a brand of meclizine, and its label lists Meclizine HCl 25 mg. Gravol's own site says dimenhydrinate is the active ingredient in all Gravol and Gravol Kids products. Both are first-generation antihistamines used for motion sickness, but they are different drugs with different label directions: the Bonine label says 1 to 2 tablets once daily, while the American dimenhydrinate label allows 1 to 2 tablets every 4 to 6 hours.
Is Bonamine vs Gravol the same comparison?
Yes. Bonamine was the Canadian brand name for meclizine, the same active ingredient as Bonine, so Bonamine vs Gravol is the meclizine vs Gravol question under an older name. Gravol is dimenhydrinate. Canadian pharmacy monographs state that meclizine is no longer manufactured for sale in Canada, so ask a pharmacist what is stocked locally.
Can you buy meclizine in Canada?
Canadian pharmacy monographs state that meclizine is no longer being manufactured for sale in Canada and is no longer available under any brand name. The Canadian brand used to be Bonamine. Some compounding pharmacies still prepare it. Availability changes, so ask your own pharmacist rather than assuming, and ask them what they would suggest instead if it is not stocked.
What is the Canadian equivalent of meclizine?
There is no direct Canadian equivalent on the shelf, because meclizine itself is what is missing. Gravol is dimenhydrinate, a different antihistamine, and it is what most Canadian shoppers end up with. A pharmacist can tell you what is available locally, including whether a compounded meclizine or a different approach makes sense for your situation.
Which makes you sleepier, Gravol or meclizine?
Compare the label wording rather than the reputation. The American dimenhydrinate label, the same ingredient as Gravol, warns that marked drowsiness may occur. The meclizine label warns that drowsiness may occur, without the word marked. Bonine's package says it is less drowsy than Dramamine, and its label still warns that you may get drowsy. Neither drug promises you will stay alert, and drowsiness is commonly reported across this class of medicine, so raise it with a pharmacist if staying awake matters for your trip.
Can I take Bonine and Gravol together?
Not without asking first. Do not combine two motion-sickness antihistamines unless a doctor or pharmacist specifically tells you to. Both can cause drowsiness, and the Bonine label says alcohol, sedatives and tranquilizers may increase drowsiness. Bring the exact packages or active-ingredient names when you ask.
Bottom line: Gravol is dimenhydrinate and meclizine is a different antihistamine, so these are two drugs rather than two names for one. The part that catches people out is where they live. In the United States both are on the shelf and the labels differ mainly in dosing interval and drowsiness wording. In Canada, Gravol is what you can buy and meclizine is not manufactured for sale there any more, which turns the comparison into a conversation with a pharmacist. And if what you actually wanted was something without an antihistamine in it, a drug-free option is available wherever you are.
Related comparisons
- Dramamine vs Gravol: are they the same medicine?
- Meclizine full guide: what it is, side effects, cautions
- Dimenhydrinate (Dramamine, Gravol) full guide
- Meclizine vs dimenhydrinate: the two antihistamines compared
- All motion sickness comparisons
Where these facts come from
- Gravol: What is dimenhydrinate? Manufacturer FAQ
- Bonine (meclizine hydrochloride) chewable tablets label, DailyMed
- Dramamine Less Drowsy (meclizine HCl 25 mg) tablets label, DailyMed
- Dramamine Original (dimenhydrinate 50 mg) tablets label, DailyMed
- Bonamine 25 mg chewable tablet, cancelled post market, Health Canada Drug Product Database
Active ingredients and label warnings were re-read at these sources in October 2026. Labels and formulations change, and they differ by country, so the box in your hand is the final word.
Informational only, and not a substitute for professional medical advice; talk to a doctor or pharmacist and follow the product label. Availability of medicines differs by country and changes over time, so confirm with a pharmacist where you are. Gravol, Dramamine, Bonine, Bonamine and other product names are trademarks of their respective owners; Dizzout (Kinda Smart Inc.) is not affiliated with or endorsed by them.