Motion sickness medications
Travelers commonly use two broad categories of motion-sickness medicine: over-the-counter antihistamines such as dimenhydrinate (Dramamine) and meclizine (Bonine), and prescription options such as the scopolamine patch and promethazine, plus regional products like cyclizine and cinnarizine. These pages are a neutral, source-backed overview of what each medicine is, its drug class, how it is generally used for motion sickness, common side effects, and who is usually advised to check with a clinician first, drawn from sources such as the FDA label, MedlinePlus/NIH, and the NHS. They are educational only, not medical advice and not dosing instructions: legal status, brand names, and availability vary by country, and whether a medicine is right for you is a decision to make with your doctor or pharmacist. Separately, Dizzout itself is a drug-free wellness app some travelers use to stay comfortable. It is not a medicine or a medical device.
Not medical advice. These pages are general educational information, not dosing instructions, and not a substitute for a doctor or pharmacist. Dizzout is not a medical provider.
Browse by medicine
- Dimenhydrinate (Dramamine)First-generation (sedating) antihistamine (H1-receptor antagonist with anticholinergic activity); OTC antiemeticBrand pages: Gravol, Gravol Kids, Gravol Immediate Release and Long Acting
- Meclizine (Bonine, Dramamine Less Drowsy)First-generation (sedating) antihistamine, piperazine class, with anticholinergic activity; antiemetic/antivertigo agentBrand pages: Bonine, Bonine MAX
- Scopolamine Patch (Transderm Scop, Scopoderm)Anticholinergic / antimuscarinic agent (belladonna alkaloid), transdermal
- Cyclizine (Valoid)First-generation (sedating) antihistamine, piperazine derivative, with antimuscarinic activity; antiemetic
- Promethazine (Phenergan, Avomine)First-generation (sedating) antihistamine, phenothiazine derivative; antiemetic with anticholinergic and sedative effects
- Cinnarizine (Stugeron)Sedating (first-generation) antihistamine with calcium-channel-blocking activity; antiemetic/antivertigo agent
- Diphenhydramine (Benadryl)First-generation (sedating) antihistamine (H1-receptor antagonist with central anticholinergic activity)
- Hyoscine Hydrobromide Tablets (Kwells, Joy-Rides)Anticholinergic / antimuscarinic agent (belladonna alkaloid), oral tablet
- Kwells (hyoscine hydrobromide)Anticholinergic / antimuscarinic agent (belladonna alkaloid), 300 microgram oral tablet
- Kwells Kids (hyoscine hydrobromide)Anticholinergic / antimuscarinic agent (belladonna alkaloid), 150 microgram children's tablet
- Joy-Rides (hyoscine hydrobromide)Anticholinergic / antimuscarinic agent (belladonna alkaloid), 150 microgram chewable tablet
- Stugeron 15 (cinnarizine)Sedating (first-generation) antihistamine with calcium-channel-blocking activity, 15 mg tablet
- Avomine (promethazine teoclate)First-generation (sedating) antihistamine, phenothiazine derivative; long-acting antiemetic, 25 mg tablet
- Buccastem (prochlorperazine)Phenothiazine antiemetic, 3 mg buccal (gum-dissolved) tablet
- Sea-Legs tablets (meclozine)First-generation (sedating) antihistamine, piperazine class; 12.5 mg tablet
- Travacalm (Original, HO, Ginger)Australian travel sickness range: antihistamine plus anticholinergic combination, hyoscine-only, and ginger tablets
- Vomikind (ondansetron)5-HT3 (serotonin) receptor antagonist antiemetic; mouth-dissolving tablets, syrup, oral strip and injection
Browse by brand
The box on the shelf carries a brand name, not an ingredient name, and one brand can hold several strengths, forms and age bands. These pages cover what is in each box and what changes between them.
- Gravol (Canadian brand)Canadian over the counter brand family. Dimenhydrinate boxes, plus a ginger line with no antihistamineSold in Canada
- Gravol Kids (ages 2 to 12)Canadian children's dimenhydrinate boxes: 15 mg chewable, 15 mg per 5 mL liquid, 25 mg suppositorySold in Canada
- Gravol Ginger (no dimenhydrinate)Canadian natural health product line. Organic ginger extract, no antihistamineSold in Canada
- Gravol Immediate Release and Long Acting capletsCanadian dual layer caplet: 25 mg immediate release plus 75 mg sustained release dimenhydrinateSold in Canada
- Bonine (US meclizine brand)US over the counter brand. Meclizine chewable tablets, 25 mg standard and 50 mg MAXSold in United States
- Bonine MAX (meclizine 50 mg)US over the counter chewable tablet. Meclizine hydrochloride 50 mg, once daily labelSold in United States
Frequently asked questions
What is the best medicine for motion sickness?
There is no single best one, because the right choice depends on how long the trip is, whether you can plan ahead, how much drowsiness you can accept, your age and your other medicines. Over the counter, dimenhydrinate (Dramamine Original) and meclizine (Bonine, Dramamine Less Drowsy) are the common choices, taken 30 to 60 minutes before travel. The scopolamine patch is a prescription option for longer trips such as cruises. The tablets work as prevention rather than rescue, and a pharmacist or doctor can match one to you.
Which motion sickness medicine is least drowsy?
Meclizine, sold as Bonine and Dramamine Less Drowsy, is usually marketed as less drowsy than dimenhydrinate (Dramamine Original), but it can still make you sleepy, so check the label before you drive. If you need to stay fully alert, the drug-free options avoid sedation entirely.
Related
- Motion sickness remedies, rankedEight remedies ordered by how fast each works and what it costs in side effects.
- Compare remedies side by sidePills, patches, wristbands, apps and natural remedies, set against each other.
- How to stop motion sicknessNine methods ranked by how quickly each works, with side effects and evidence.
- What is motion sickness?The mechanism: why the inner ear and the eyes disagree, and who gets it most.
This page is for general educational and informational purposes only. It is not medical advice and is not a substitute for the advice of a qualified healthcare professional. Dizzout is not a medical provider: we are not doctors or pharmacists. The information here is a general summary drawn from sources such as the FDA-approved label and other public health resources, and it may not reflect the most current changes; the official product label is the authoritative source. Whether any medicine is right for you, and how much to take, are individual decisions that depend on your health, age, and other medicines. We do not provide dosing instructions: always read the product label and follow its directions. Talk to your doctor or pharmacist before starting, stopping, or changing any medication, and never disregard or delay professional medical advice because of something you read here. If you think you may have a medical emergency, contact a doctor or your local emergency number immediately.